Hong Kong Newswire April 9
University of Hong Kong released research scholars novel coronavirus may cause more severe lung damage than the SARS virus. They found that for the first time how the novel coronavirus cause lung disease, and why it spread to other organs; also found that interferon can inhibit virus replication in the lungs future treatment strategy of the new revelation.
HKU research team using human respiratory tract tissue cultivated in vitro, a relatively new type of coronavirus, SARS coronavirus and the causes of the common cold symptoms human coronavirus infection. Relevant outcomes recently published in the International Journal of Virology Virology Journal "(Journal of Virology).
The study shows that the new type of coronavirus replication in human speed faster than the SARS coronavirus. Novel coronavirus that can infect human lungs, patients with breathing difficulties, and hinder the recovery process in the lungs of patients after repair and infection.
Novel coronavirus infection in pulmonary vascular endothelial cells, the virus a chance to spread through the blood to the organs outside the respiratory tract, causing more severe lung damage than the SARS coronavirus in patients.
The study also found that, the novel coronavirus avoid damage lung interferon activation response of lung cells. Interferon system of human first line of defense against virus infection.Therefore, the study with interferon therapy, and pulmonary viral replication can be effectively suppressed. This treatment will help treatment programs for future clinical studies of human infection with the novel coronavirus important revelation.
Influenza Research Center of the University of Hong Kong Li Ka Shing Faculty of Medicine School of Public Health, Department of Pathology and State Key Laboratory of Emerging Infectious Diseases scholars led the study.
The novel coronavirus commonly known as "SARS", found that cases of human infection from the global total of 17 confirmed human cases, with 11 deaths, a number of patients from the Middle East since April 2012. Has new coronavirus spread of the virus and the disease mechanisms are not yet completely understood. (End) http://www.hkcna.hk//content/2013/0409/186548.shtml
