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Wednesday, February 5, 2014

H7N9 virus mutates eyeing the young is it?

Thursday, February 06, 2014 June 02

Shanghai doctor died only 31 years old this year, there are eight Zhejiang patients less than 50 years old
H7N9 virus mutates eyeing the young is it?
Experts said there is no evidence of human to human transmission

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This year, the country has confirmed cases of human infection with H7N9 avian influenza 110 cases, 20 cases including Zhejiang, Guangdong, Shanghai death. Recently, our new weekly number of cases of human infection confirmed H7N9 bird flu outbreaks have been close to peak levels during the last year. Although the disease control experts noted that during the Spring Festival is not an outbreak of human infection with H7N9 bird flu, but the reporter Statistics found, H7N9 bird flu has been dropping. Only in Zhejiang Province, 26 cases infected in 8 patients younger than 50 years old. The youngest only 20 years old. Shanghai due to H7N9 avian influenza has been reported in the doctor's death, but also only 31 years old.
H7N9 bird flu tentacles young, because H7N9 virus mutates it? Relatively resistant to young people, why encounter the virus, also fall so fast?
Why multiply the young patients
Young families do not lianzhouzhuan overtime
In Zhejiang, for example, this year's bird flu confirmed in 26 patients, the reporter carefully divided about their ages: 20 to 29 years, 2; 30 to 39 years, 4; 40 to 49 years, 2; 50 to 59 years, 8; 60 to 69 years old, 5; 70 to 79 years old, 5 people. If you draw a line at 50 years old, young patients below 8 people; elderly patients above 18 people.
Overall, though, this year's H7N9 bird flu virus, and there is no special "preference" of young people, the proportion of infections of all ages, not particularly noticeable differences. But the young man must not be taken lightly, can not be considered independent of H7N9 avian influenza with their own, or they will be very dangerous.
Zhejiang University Hospital of Infectious Diseases Professor Liang Weifeng reminded that the young man looked at the body strong, but now to the end of the year, people with a lot of overtime, after some "lianzhouzhuan" office workers, fatigue, colds,
It is easy to let the H7N9 avian influenza virus has an opportunity.
So experts recommend: Young cold not carrying, be sure to pay attention to rest, drink plenty of water, so that the body's immune system to restore as soon as possible, so as to fight with the virus. If there is a continuous fever, it is best to go to hospital blood test, if not high leukocyte index, lung inflammation, and have had contact with poultry experience, the best retest H7N9 virus nucleic acid.
H7N9 virus could mutate it?
There is no evidence of human to human transmission, but still wary
Young filed, Shanghai doctors infection cases occurred, and the doctors have not come into contact with poultry, should H7N9 bird flu virus is showing signs of mutation? Reporter put the question thrown Professor Lu Hongzhou, deputy director of Shanghai Public Health Clinical Center.
Professor Lu Hongzhou said to now, there are no cases of extraordinary human transmission of avian influenza H7N9 occurred.
Late last year, Zhejiang Huzhou Wengxu there had been infected with H7N9 avian influenza have been confirmed cases, then, Li Lanjuan academician after consultation with relevant experts believe that between them are not mutually infected, there is no evidence of human to human transmission.
However, Professor Lu Hongzhou alert, H7N9 avian influenza virus from person to person in a limited capacity exists in theory, he repeatedly stressed that this feature has been recognized by the national authority of the experts. "The so-called limited human-to-human transmission capacity, is characterized by the level of gene sequencing of the virus up analysis." Professor Lu said.
It is reported that the gene sequence of H7N9 avian influenza virus has been announced. This is the last one from the Zhejiang University, State Key Laboratory diagnosis of infectious diseases hospital director Li Lanjuan academicians, isolated and uploaded to international genebanks.
Professor Lu Hongzhou told reporters that since the H7N9 bird flu virus since appeared, one of the country's experts are most concerned about is the thing, there is no monitoring of H7N9 virus mutation key nodes occur.
He believes that the new H7N9 virus in the blood
Coagulation fibroin, the 226th amino acid particularly critical amino acids of this site has the typical characteristics of the human influenza virus genes. Professor Lu Hongzhou, once the site of mutation, meaning the virus and human respiratory epithelial cells are easily combined, people may greatly increase the chance of infection, which is the successor of the will of people.
"This change will come when nobody predicted, but vigilance is necessary." Professor Lu Hongzhou said.
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According to Voice of China reported that the current virus is still no significant variation occurred. Currently H7N9 is still a sporadic, Zhejiang, Guangdong and other southern provinces relatively high.
China CDC epidemiology professor Zeng Guang, chief expert believes that the virus occurred in areas which have some chance; Feng Zijian, deputy director of the Centre stressed that three terms, H7N9 virus either from epidemiological or virological , are currently found no significant variation.
These three aspects: one is the ability to communicate is not more easily transmitted from birds to humans, is not it easier person to person? This has not changed, with seeing the same situation last year; second is independent of the variation is not more powerful? Lead to more serious after the onset? Severe cases and deaths occur more of? This situation did not appear; third is to see there is no antiviral drug resistance mutation. It still is alkyl resistant class of drugs, the neuraminidase inhibitors of drug sensitive. In other words, three aspects are not concerned about the variability of new changes.  http://translate.google.com/translate?sl=zh-CN&tl=en&js=n&prev=_t&hl=en&ie=UTF-8&u=http%3A%2F%2Fwww.yznews.com.cn%2Fyzsbs%2Fhtml%2F2014-02%2F06%2Fcontent_543415.htm