Guangdong ten-day reports of human infection with H7N9 cases

were 12 cases of death

Source: 21CN 2014-02-06 09:17

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Keywords: Guangdong ten consecutive days, reports of human infection with H7N9 cases, 12 cases of death

Yesterday, the Ministry of Health and Family Planning Commission official website of the latest Bulletin, Zhaoqing, Foshan, Shenzhen City, a total of three new H 7N 9 4 cases of avian influenza confirmed cases of human infection. Guangdong has reported confirmed cases of consecutive days, as of yesterday, Guangdong has reported 54 cases of human infection with H 7N 9 confirmed cases and 12 deaths.
 
According to statistics, Guangdong Province, Huizhou, since August 2013 the first reported case since, as of February 5, 2014, 54 cases were reported in Guangdong Province cases, cured 16 cases, 12 deaths (were living in Dongguan, Yangjiang, Guangzhou , Jiangmen, Meizhou, Foshan, Huizhou and Shenzhen). Statistics by patient residence, located in Guangzhou, six cases of cases, 17 cases in Shenzhen, Foshan and 10 cases, 4 cases of Huizhou, Dongguan three cases, four cases of Yangjiang, Meizhou one case, two cases of Jiangmen, Zhaoqing five cases, Zhongshan two cases.
 
Under the notification, new cases of the following people:
● Lee, female, 5 years old, now living Huaiji County, Zhaoqing City, February 4 confirmed that the current stable condition.
● Liang Yijun, male, 42 years old, workers, now living Huaiji County, Zhaoqing City, February 4 diagnosed, currently in critical condition.
● strict, male, 49 years old, self-employed, now living Gaoming District of Foshan City. February 4 confirmed that the current stable condition.
● Dengmou, male, 56 years old, unemployed, now living Longhua District. February 4 diagnosed, currently in critical condition.
 
Prevention and control
Lin Shaochun hosted epidemic prevention and control of human infection with the H7N9 leadership team meetings
Once localized outbreaks live bird markets firmly closed
Southern News reporter Xue Bing Ni yesterday afternoon, the provincial vice governor Lin Shaochun hosted the prevent
...
Expert
Flu-like symptoms to tell the history of exposure to poultry
Experts advise to wash your hands as soon as possible after contact with live poultry, etc.
Southern News reporter Wang Chengbo for H 7N 9 confirmed cases of human bird flu infection consecutive Shenzhen CDC experts said that the current situation is still sporadic, does not appear clusters of outbreaks, there is no evidence that can be pers...
 

Shenzhen diagnosed 18 cases of eight people live in the Longgang District
Southern News yesterday, the Shenzhen soared H 7N 9 confirmed cases of avian influenza infection in a person. Shenzhen diagnosed 18 cases (including Dongguan confirmed cases in the deep) lived in Longgang 8 cases. The youngest was 6 years old boy, who was 82 years old maximum.
Southern reporter Statistics found in Shenzhen have been seven confirmed cases were cured, one person died and 10 people in the existing hospital. In confirmed cases, 8 cases occurred in Longgang District, mainly in the South Bay, Phuket, two streets, Luohu District 4 cases. Futian District and Bao'an District have two cases, Longhua District 1 case, another case was diagnosed in Shenzhen, Dongguan.
Outbreak Communications
 
Zhejiang
Augmented by a further four cases
Southern News Zhejiang Provincial Health and Family Planning Commission Feb. 5 briefing, the province added four cases of human infection of bird flu H 7N 9, both February 4 confirmed cases, of which two were male, two were female; 3 condition is Severe, a man critically ill; 4 people minimum age was 35 years and a maximum of 67 years; currently three people in Hangzhou, a hospital, a man in Shaoxing, a hospital for treatment.
It is reported that since 2014, 71 cases have been confirmed in Zhejiang H 7N 9 people infected with bird flu. (New)
 
Fujian Province
Increased to 14 cases
 
Health and Family Planning Commission of Fujian Province, according to Xinhua News Agency, February 4 notification, the date of the new province confirmed case of human infection of bird flu H 7N 9. Currently, Fujian Province, people infected with H 7N 9 avian flu cases has increased to 14 cases. New cases are: patients Moumou, aged 36, mechanic, now living in Quanzhou Yongchun County, is currently in critical condition at a hospital in Quanzhou, isolation and treatment.
 
Guangxi
Diagnosed one case
According to Xinhua News Agency reporter on the 5th learned from the health department of Guangxi, Guangxi confirmed case of human infection of bird flu H 7N 9. Patients Li Moumou, female, 41 years old, Heng Xu Zhen Tao people since January 27 flu symptoms in Zhongshan City, Guangdong, January 28 back Heng, February 3 due to exacerbations Heng a hospital for treatment. Currently, patients in critical condition.
 
National guard Planning Commission:
Found no H7N9 virus from person to person
 
During the Spring Festival, according to Xinhua News Agency, the National Health and Family Planning Commission to actively guide the country to carry out human infection of bird flu H 7N 9 treatment and prevention work. Up to now, the vast majority of cases remain sporadic, the ability to have an effective human to human transmission of the virus was not found.
January 30, the National Health and Family Planning Commission held H 7N 9 people infected with bird flu prevention and control of the Leading Group Office meeting, on a really good job of cases during the Spring and early detection and treatment of severe cases where work has been re-deployed.
New cases of H7N9 nationwide yesterday
Zhejiang
Add four cases
2 male and 2 female
Fujian Province
Add one case
1 M
Guangdong
Add four cases
3 male and 1 female
Guangxi
Diagnosed one case
1 woman   http://translate.google.com/translate?sl=zh-CN&tl=en&js=n&prev=_t&hl=en&ie=UTF-8&u=http%3A%2F%2Fnews.yesky.com%2Fhot%2F306%2F35977806.shtml

H7N9: Each case must be informed, science and do not absence [2014-02-06]

Source: Netease news 2014-02-06 08:50

H7N9 briefing every case lead to "talk bird phobia"-style panic, the reason lies in the disclosure of information asymmetry: although normalization notification mechanism, but the corresponding science remained scarce.
Affected by H7N9, Guangdong and other places of live poultry sales slump, the poultry industry suffered heavy losses. Recently, Guangdong and other places poultry industry associations, companies jointly submitted an open letter to all levels of government, the request "to stop the implementation of each notification H7N9 cases, to avoid the outbreak of ultra-dense reports." Guangdong health department responded, "no legal basis to stop notification", but the outbreak information to the media downplayed the beginning: no longer active communication of information to the media to send cases, notification no longer appears in the word "live poultry contact history" and so on... http://translate.googleusercontent.com/translate_c?depth=1&hl=en&ie=UTF8&prev=_t&rurl=translate.google.com&sl=zh-CN&tl=en&u=http://news.yesky.com/hot/150/35977650.shtml&usg=ALkJrhjeEk5AgHU6kp6PSEmaOAgroJmBUQ

H7N9 virus mutates eyeing the young is it?

Thursday, February 06, 2014 June 02

Shanghai doctor died only 31 years old this year, there are eight Zhejiang patients less than 50 years old H7N9 virus mutates eyeing the young is it? Experts said there is no evidence of human to human transmission Profile picture This year, the country has confirmed cases of human infection with H7N9 avian influenza 110 cases, 20 cases including Zhejiang, Guangdong, Shanghai death. Recently, our new weekly number of cases of human infection confirmed H7N9 bird flu outbreaks have been close to peak levels during the last year. Although the disease control experts noted that during the Spring Festival is not an outbreak of human infection with H7N9 bird flu, but the reporter Statistics found, H7N9 bird flu has been dropping. Only in Zhejiang Province, 26 cases infected in 8 patients younger than 50 years old. The youngest only 20 years old. Shanghai due to H7N9 avian influenza has been reported in the doctor's death, but also only 31 years old. H7N9 bird flu tentacles young, because H7N9 virus mutates it? Relatively resistant to young people, why encounter the virus, also fall so fast? Why multiply the young patients Young families do not lianzhouzhuan overtime In Zhejiang, for example, this year's bird flu confirmed in 26 patients, the reporter carefully divided about their ages: 20 to 29 years, 2; 30 to 39 years, 4; 40 to 49 years, 2; 50 to 59 years, 8; 60 to 69 years old, 5; 70 to 79 years old, 5 people. If you draw a line at 50 years old, young patients below 8 people; elderly patients above 18 people. Overall, though, this year's H7N9 bird flu virus, and there is no special "preference" of young people, the proportion of infections of all ages, not particularly noticeable differences. But the young man must not be taken lightly, can not be considered independent of H7N9 avian influenza with their own, or they will be very dangerous. Zhejiang University Hospital of Infectious Diseases Professor Liang Weifeng reminded that the young man looked at the body strong, but now to the end of the year, people with a lot of overtime, after some "lianzhouzhuan" office workers, fatigue, colds, It is easy to let the H7N9 avian influenza virus has an opportunity. So experts recommend: Young cold not carrying, be sure to pay attention to rest, drink plenty of water, so that the body's immune system to restore as soon as possible, so as to fight with the virus. If there is a continuous fever, it is best to go to hospital blood test, if not high leukocyte index, lung inflammation, and have had contact with poultry experience, the best retest H7N9 virus nucleic acid. H7N9 virus could mutate it? There is no evidence of human to human transmission, but still wary Young filed, Shanghai doctors infection cases occurred, and the doctors have not come into contact with poultry, should H7N9 bird flu virus is showing signs of mutation? Reporter put the question thrown Professor Lu Hongzhou, deputy director of Shanghai Public Health Clinical Center. Professor Lu Hongzhou said to now, there are no cases of extraordinary human transmission of avian influenza H7N9 occurred. Late last year, Zhejiang Huzhou Wengxu there had been infected with H7N9 avian influenza have been confirmed cases, then, Li Lanjuan academician after consultation with relevant experts believe that between them are not mutually infected, there is no evidence of human to human transmission. However, Professor Lu Hongzhou alert, H7N9 avian influenza virus from person to person in a limited capacity exists in theory, he repeatedly stressed that this feature has been recognized by the national authority of the experts. "The so-called limited human-to-human transmission capacity, is characterized by the level of gene sequencing of the virus up analysis." Professor Lu said. It is reported that the gene sequence of H7N9 avian influenza virus has been announced. This is the last one from the Zhejiang University, State Key Laboratory diagnosis of infectious diseases hospital director Li Lanjuan academicians, isolated and uploaded to international genebanks. Professor Lu Hongzhou told reporters that since the H7N9 bird flu virus since appeared, one of the country's experts are most concerned about is the thing, there is no monitoring of H7N9 virus mutation key nodes occur. He believes that the new H7N9 virus in the blood Coagulation fibroin, the 226th amino acid particularly critical amino acids of this site has the typical characteristics of the human influenza virus genes. Professor Lu Hongzhou, once the site of mutation, meaning the virus and human respiratory epithelial cells are easily combined, people may greatly increase the chance of infection, which is the successor of the will of people. "This change will come when nobody predicted, but vigilance is necessary." Professor Lu Hongzhou said. ■ Related Links According to Voice of China reported that the current virus is still no significant variation occurred. Currently H7N9 is still a sporadic, Zhejiang, Guangdong and other southern provinces relatively high. China CDC epidemiology professor Zeng Guang, chief expert believes that the virus occurred in areas which have some chance; Feng Zijian, deputy director of the Centre stressed that three terms, H7N9 virus either from epidemiological or virological , are currently found no significant variation. These three aspects: one is the ability to communicate is not more easily transmitted from birds to humans, is not it easier person to person? This has not changed, with seeing the same situation last year; second is independent of the variation is not more powerful? Lead to more serious after the onset? Severe cases and deaths occur more of? This situation did not appear; third is to see there is no antiviral drug resistance mutation. It still is alkyl resistant class of drugs, the neuraminidase inhibitors of drug sensitive. In other words, three aspects are not concerned about the variability of new changes.  http://translate.google.com/translate?sl=zh-CN&tl=en&js=n&prev=_t&hl=en&ie=UTF-8&u=http%3A%2F%2Fwww.yznews.com.cn%2Fyzsbs%2Fhtml%2F2014-02%2F06%2Fcontent_543415.htm

Cases of New Deadly Bird Flu Surge in China, Experts Say

By DONALD G. McNEIL Jr.FEB. 4, 2014

Cases of the new H7N9 avian influenza in China are surging alarmingly, flu experts warned this week.

There are now about 300 confirmed cases, with more appearing every day. Roughly a quarter of the victims have died.

The first human cases were reported only last March. By contrast, the H5N1 influenza virus, another lethal strain that jumped from birds to people, first appeared in 2003 and took almost five years to reach the 300-case mark.

“H7N9 is blowing right by H5N1,” said Michael T. Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota. “I’m really worried about that.”

At the same time, an even newer avian flu in China has killed its first human victim. That strain, known as H10N8, has been confirmed in only two people — a 73-year-old woman who died in December but whose infection was confirmed later, and a 55-year-old woman from the same province hospitalized in January. Both had contact with live poultry.

(Influenzas are described by the shapes of two protuberances on their surfaces: the hemagglutinin “spike,” or “H,” that attaches to cells, and the neuraminidase “helicopter,” or “N,” that chops off receptors, allowing new viruses to escape. There are 18 known types of H and 11 of N.)

While the newer influenza virus is worrisome, a mere two cases is “a far, far cry” from the risk posed by H7N9, said Ruben Donis, chief of preparedness for the flu division of the Centers for Disease Control and Prevention. He noted that the H7N9 virus had infected people in 10 Chinese provinces and was close to the borders of Vietnam, Cambodia and other poor Southeast Asian nations less adept than China at flu surveillance.

Birds appear to be spreading the H7N9 virus more through their breath than through feces, the normal infection route, Dr. Osterholm said, which means that fecal-sample testing in live markets may miss cases.

Monitoring the spread of the H7N9 and H10N8 viruses is difficult because neither makes chickens sick. Poultry farmers resist testing because a positive test forces them to destroy flocks that appear healthy. By contrast, the H5N1 virus rapidly kills flocks, so farmers want it extinguished.

Although human-to-human transmission of the H7N9 virus has not been confirmed, there have been clusters of two or three cases within families.

Because some relatives were reported to have developed symptoms days later than others, Henry L. Niman, a flu watcher in Pittsburgh who monitors news reports, said the most likely explanation was that they infected each other.

Dr. Osterholm disagreed, saying family members could have been exposed to the same birds but fallen ill on different days.  http://www.nytimes.com/2014/02/05/health/cases-of-new-deadly-bird-flu-surge-in-china-experts-say.html?_r=0

Human infection with avian influenza A(H7N9) virus – update

Disease outbreak news

5 February 2014 - On 4 February 2014, the National Health and Family Planning Commission (NHFPC) of China notified WHO of eight additional laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus, including two deaths. .

Details of the cases are as follows

Six of the cases are male. The age range is 4 to 84 years old. Cases were reported from Zhejiang (4), Guangdong (3) and Jiangsu (1). Three cases are currently in a critical condition, two cases are currently in a severe condition and one is currently in a mild condition. All cases are reported to have had a history of exposure to poultry or a live poultry market.

• A 42 year-old man from Hangzhou City, Zhejiang Province, who became ill on 25 January and was admitted to hospital on 30 January. He is currently in a severe condition. The patient has a history of exposure to poultry.
• An 84 year-old man from Hangzhou City, Zhejiang Province, who became ill on 24 January and was admitted to hospital on 28 January. He is currently in a critical condition. The patient has a history of exposure to poultry.
• A 56 year-old man from Jinhua City, Zhejiang Province, who became ill on 24 January and was admitted to hospital on 1 February. He is currently in a severe condition. The patient has a history of exposure to a live poultry market.
• A 51 year-old man from Shaoxing City, Zhejiang Province, who became ill on 27 January and was admitted on 1 February. He is currently in a critical condition. The patient has history of exposure to a live poultry market.
• A 4 year-old girl from Zhaoqing City, Guangdong Province, who became ill on 26 January and was admitted to hospital on 3 February. She is currently in a mild condition. The patient has a history of exposure to live poultry.
• A 76 year-old man from Yangjiang City, Guangdong Province, who became ill on 27 January and was admitted to hospital on 1 February. He died on 3 February. The patient had a history of exposure to live poultry.
• A 52 year-old man from Huizhou City, Guangdong Province, who became ill on 25 January and was admitted to hospital on 2 February. He died on 3 February. The patient had a history of exposure to live poultry.
• A 59 year-old woman from Wuxi City, Jiangsu Province, who became ill on 26 January and was admitted to hospital on 29 January. She is currently in a critical condition. The patient has history of exposure to a live poultry market.

So far, there is no evidence of sustained human-to-human transmission.
The Chinese Government continues to take the following surveillance and control measures:

• strengthen surveillance and situation analysis;
• reinforce case management and treatment;
• conduct risk communication with the public and release information;
• strengthen international collaboration and communication; and
• conduct scientific studies.

Sporadic human cases

While the recent report of avian influenza A(H7N9) virus being detected in live poultry imported from the mainland to Hong Kong SAR, shows the potential for the virus to spread through live poultry, at this time there is no indication that international spread of avian influenza A(H7N9) has occurred through humans or animals.
Further sporadic human cases of A(H7N9) infection are expected in affected and possibly neighbouring areas, especially given expected increases in the trade and transport of poultry associated with the Lunar New Year.

WHO advice

WHO advises that travellers to countries with known outbreaks of avian influenza should avoid poultry farms, or contact with animals in live bird markets, or entering areas where poultry may be slaughtered, or contact with any surfaces that appear to be contaminated with faeces from poultry or other animals. Travellers should also wash their hands often with soap and water. Travellers should follow good food safety and good food hygiene practices.
WHO does not advise special screening at points of entry with regard to this event, nor does it currently recommend any travel or trade restrictions.
As always, a diagnosis of infection with an avian influenza virus should be considered in individuals who develop severe acute respiratory symptoms while travelling or soon after returning from an area where avian influenza is a concern.
WHO encourages countries to continue strengthening influenza surveillance, including surveillance for severe acute respiratory infections (SARI) and to carefully review any unusual patterns, in order to ensure reporting of human infections under the IHR (2005), and continue national health preparedness actions.

Current technical information as well as guidance related to avian influenza A(H7N9) can be found at the WHO web site:

• Avian influenza A(H7N9) virus
• Human infections with avian influenza A(H7N9) virus
  pdf, 194kb
  21 January 2014
• World - Avian influenza in humans
• Live food markets: Reducing the risk of influenza virus transmission from animals   
• lhttp://www.who.int/csr/don/2014_02_05bis/en/index.html 

China reports 11 new H7N9 human cases

English.news.cn 2014-02-05 21:56:45

BEIJING, Feb 5 (Xinhua) -. Eleven Chinese people were confirmed to be infected with the H7N9 bird flu on Wednesday in four regions, with 8 in critical condition, according to local health authorities.
The southern province of Guangdong reported 4 new cases, including a 5-year-old girl and a 42-year-old man in Zhaoqing City, a 49-year-old man in Foshan City and a 56-year-old man in Shenzhen City, said the provi...  http://translate.googleusercontent.c...Up4gR66lke-I_g

Zhejiang, one week notified 13 new cases of human H7N9 avian influenza infection

Xinhua Hangzhou, February 5 (Reporter Zhang Le) reporter on the 5th from the Zhejiang Provincial Health and Family Planning Commission was informed that since January 30 to February 5, Zhejiang notified added 13 cases of human infection with H7N9 avian influenza.
So far, this year, Zhejiang has a total 69 cases of human infection with the H7N9 briefing bird flu epidemic continued to show a high degree of dissemination of state.
Water certain patients, male, 75 years old, farmer, Yinzhou District, Ningbo people. January 30 was infected with H7N9 briefing confirmed human cases of avian influenza. Is now in critical condition, a hospital for treatment in Ningbo.
Patients Lin Moumou, male, 76 years old, retired, Zhenhai District, Ningbo people. January 30 was infected with H7N9 briefing confirmed human cases of avian influenza. Now the condition is severe, in Ningbo, a hospital for treatment.
In certain patients, male, 78 years old, farmer, Yuhang District of Hangzhou people. January 30 was infected with H7N9 briefing confirmed human cases of avian influenza. Is now in critical condition, in Hangzhou, a hospital for treatment.
Patients Moumou, male, 64 years old, retired, Jiangbei District, Ningbo people. January 30 was infected with H7N9 briefing confirmed human cases of avian influenza. Is now in critical condition, a hospital for treatment in Ningbo.
Patients You Moumou, male, 44 years old, farmer, Taizhou Huangyan people. February 2 was notified diagnosed human cases of avian influenza H7N9 infection. Now the condition is severe, in Taizhou, a hospital for treatment.
Patients Mo XX, male, 42 years old, Binjiang District, Hangzhou people. February 4 confirmed human infections have been notified cases of avian influenza H7N9. Now the condition is severe, treatment in a hospital in Hangzhou.
Patients Han Moumou, male, 84 years old, Yuhang District of Hangzhou people. February 4 confirmed human infections have been notified cases of avian influenza H7N9. Is now in critical condition at a hospital in Hangzhou treatment.
Patients Wu Moumou, male, 56 years old, Wu Jinhua city people. February 4 confirmed human infections have been notified cases of avian influenza H7N9. Now the condition is severe, treatment in a hospital in Hangzhou.
Money certain patients, male, 51 years old, Shaoxing Bridge District people. February 4 confirmed human infections have been notified cases of avian influenza H7N9. Is now in critical condition at a hospital in Hangzhou treatment.
February 5th, Zhejiang Provincial Health and Family Planning Commission informed the four cases of infection.
Patients Lin Moumou, male, 67 years old, Shaoxing City people. Now the condition is severe, treatment at a hospital in Shaoxing.
Patients Wu Moumou, female, 35 years old, Pingyang County, Wenzhou people. Now the condition is severe, treatment in a hospital in Hangzhou.
Patients Ma Moumou, female, 59 years old, Hangzhou, Fuyang City People. Now the condition is severe, treatment in a hospital in Hangzhou.
Patients Xu X, male, 49 years old, now living Gongshu. Is now in critical condition at a hospital in Hangzhou treatment.  http://translate.googleusercontent.com/translate_c?depth=2&hl=en&ie=UTF8&prev=_t&rurl=translate.google.com&sl=auto&tl=en&u=http://news.xinhuanet.com/2014-02/05/c_119216384.htm&usg=ALkJrhiSjwBXgo3sEBREw7z79WdWcK3c4g

Guangxi boy confirmed with H7N9 virus after mother contracts bird flu

..Health authorities in Guangxi province confirmed a boy had contracted the H7N9 strain of bird flu, a day after his mother was confirmed to have the virus.
The Guangxi health bureau said the boy, aged five and from Hengxian county, Nanning, started to show symptoms on Monday and was diagnosed with having the disease on Wednesday.
Health officials are still determining how the boy became infected but said he had been in close contact with his mother, 41.
She began to feel unwell late last month after visiting Zhongshan in Guangdong province. She returned to Nanning on January 28.
The boy remained in a stable condition but his mother’s condition was critical.
Xinhua reported the national health commission said there was no proof the H7N9 was spreading sustainably from person to person.... http://www.scmp.com/news/china/article/1421673/guangxi-boy-confirmed-h7n9-virus-after-mother-contracts-bird-flu

Made for China? Research Says H7N9 Flu Virus Confined Only to Chinese

OK..If you say so...

By Esther Tanquintic-Misa | February 4, 2014 4:59 PM EST

Because of a susceptibility gene, emerging and getting rampant H7N9 flu virus may only infect residents of China.
A report published in the journal Clinical Infectious Diseases by Dr David Hui of the Chinese University of Hong Kong said H7N9 flu virus spreads easily and more among the Chinese because of the IFITM3 gene (interferon-induced transmembrane protein-3 gene).

View Full Image

REUTERS Health officials in protective suits put a goose into a sack as part of preventive measures against the H7N9 bird flu at a poultry market in Zhuji, Zhejiang province January 5, 2014. The local government ordered all live poultry be killed at two markets in Zhuji after a 34-year-old woman was confirmed to be infected with the H7N9 virus on Saturday, local media reported. Picture taken January 5, 2014.

The IFITM3 gene is the one that increases influenza disease severity. It is more predominant among the Chinese people. Caucasians hardly have them, Mr Hui said.
This seemed to confirm an earlier study that said one factor the Chinese are susceptible to the H7N9 flu virus was because they have lower levels of an immune protective mechanism known as CD8+ T lymphocyte (CTL) immunity.
Dr Hui said that 70 per cent of Chinese patients who had experienced severe influenza infection had the IFITM3 susceptibility gene, which could explain the emergence or presence of infection clusters among family members.
"Because the risk genotype occurs with such a high frequency [in Chinese people], its effect translates to a large population-attributable risk of 54.3% for severe infection in the Chinese population studied compared with 5.4% in Northern Europeans," Dr Hui said.

On Tuesday, China reported two new deaths due to the H7N9 flu virus. The death tally has now reached a total of 25 since January, while the number of human infections has reached 113 cases. Zhejiang and Guangdong were the areas most affected.
The new H7N9 virus emerged only last spring.  http://au.ibtimes.com/articles/537199/20140204/china-research-h7n9-flu-virus.htm#.UvGjtfttaCk

CAMBODIA-First H5N1 case of 2014 reported

Wed, 5 February 2014

Daniel Pye

A 5-year-old boy has tested positive for avian influenza, making the toddler the first reported case this year, the Ministry of Health and the World Health Organization said yesterday.
The boy, from Kampong Thom province’s Stung Sen district, was confirmed positive for the H5N1 virus on Sunday, the statement said.
The boy is in a stable condition after being admitted to the Jayavarman VII Hospital in Siem Reap town.
A government investigation into the case revealed that 200 chickens had mysteriously died in the boy’s village in mid-January, after which his parents had prepared the expired birds to eat.
“I urge parents and guardians to keep children away from sick or dead poultry and prevent them from playing with chickens or ducks,” Minister of Health Mam Bunheng said in the statement.
At least 22 cases of bird flu were recorded in Cambodia last year, according to the Ministry of Health. http://www.phnompenhpost.com/national/first-h5n1-case-2014-reported

JX346

They isolated the virus and dubbed it A/Jiangxi-Donghu/346/2013(H10N8), or JX346 for short...

Genetic findings

The authors' genomic analysis of the virus showed that its hemagglutinin (H) protein was most closely related to that of a 2012 H10N3 duck isolate from Hunan province and that the neuraminidase (N) protein was most closely related to that of an H10N8 virus from a mallard in Korea.

All six of JX346's internal genes were closely related to those of H9N2 poultry viruses currently circulating in China, the authors found. But the internal genes were significantly different from those of previously reported H10 and N8 subtype viruses and were in different subclades from those of known H7N9 viruses.
Only two H10N8 viruses have been reported previously in China, one from a lake and the other from a poultry market, the report notes.

"H9N2 virus provided the internal genes not only for the H10N8 virus, but also for H7N9 and H5N1 viruses," the report says. "This relation should be studied further to understand the mechanism of how the internal genes of H9N2 virus transfer to viruses that infect people, and how the avian influenza virus transfers between species."
The authors say the findings suggest that JX346 might have originated from multiple reassortments between different avian flu viruses.

Senior author Yuelong Shu, PhD, of the Chinese Center for Disease Control and Prevention commented in a Lancet press release, "The H10 and H8 gene segments might have derived from different wild bird influenza viruses [that] reassorted to give rise to a hypothetical H10N8 virus in wild birds, which infected poultry and then reassorted with H9N2 viruses in poultry to give rise to the novel reassortant JX346 (H10N8) virus."
In other observations, the researchers say the patient's chronic medical conditions could have played a role in her death. But they found that the novel virus was "overwhelmingly dominant" in her tracheal specimens, which indicates that it was involved in her demise.

In addition, they found a mixture of glutamic acid and lysine at residue 627 in the virus's PB2 protein, a mutation that is associated with adaptation to, and can increase virulence in, mammals.
Further, the authors report that the novel virus preferentially binds avian-like alpha2,3-linked sialic acid receptors, which are "dominant in human lung tissue," suggesting a potential for the kind of lung damage found in human H5N1 infections....

http://www.cidrap.umn.edu/news-perspective/2014/02/study-h10n8-virus-first-human-case-novel-strain

The Lancet, Early Online Publication, 5 February 2014

Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study

Background

Human infections with different avian influenza viruses—eg, H5N1, H9N2, and H7N9—have raised concerns about pandemic potential worldwide. We report the first human infection with a novel reassortant avian influenza A H10N8 virus.

Methods

We obtained and analysed clinical, epidemiological, and virological data from a patient from Nanchang City, China. Tracheal aspirate specimens were tested for influenza virus and other possible pathogens by RT-PCR, viral culture, and sequence analyses. A maximum likelihood phylogenetic tree was constructed.

Findings

A woman aged 73 years presented with fever and was admitted to hospital on Nov 30, 2013. She developed multiple organ failure and died 9 days after illness onset. 

 

 A novel reassortant avian influenza A H10N8 virus was isolated from the tracheal aspirate specimen obtained from the patient 7 days after onset of illness.

 

Sequence analyses revealed that all the genes of the virus were of avian origin, with six internal genes from avian influenza A H9N2 viruses. The aminoacid motif GlnSerGly at residues 226—228 of the haemagglutinin protein indicated avian-like receptor binding preference. A mixture of glutamic acid and lysine at residue 627 in PB2 protein—which is associated with mammalian adaptation—was detected in the original tracheal aspirate samples. 

 

The virus was sensitive to neuraminidase inhibitors. Sputum and blood cultures and deep sequencing analysis indicated no co-infection with bacteria or fungi. Epidemiological investigation established that the patient had visited a live poultry market 4 days before illness onset.

Interpretation

The novel reassortant H10N8 virus obtained is distinct from previously reported H10N8 viruses. The virus caused human infection and could have been associated with the death of a patient.

Funding

Emergency Research Project on human infection with avian influenza H7N9 virus, the National Basic Research Program of China, and the National Mega-projects for Infectious Diseases. 

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2814%2960111-2/fulltext

Bird Flu Case Appears In Bali

  Wednesday, February 5, 2014 | 7:50

[Denpasar] The case of bird flu or H5N1 virus occurred in Klungkung regency, Bali, precisely in the area of ​​the Strait of Hamlet, Village Banjarangkan.
....Dozens of chickens had died suddenly in this area some time ago. In fact, a chicken owner, Ketut Ward (40) could dispose of dead chickens without using protection.

As a result, Ketut Ward has a fever, and eventually had to be taken to the general hospital center (Dr) Sanglah for allegedly contracted the bird flu virus.

"From rapid tests carried out by the department of Fisheries and marine farms (Diskanlut) Klungkung District, stated that the dead chickens infected with the bird flu virus positive. Monday Yesterday, we had lalukan tests with animal husbandry department, and the chicken was positive, but the person is still in test and treated at Sanglah Hospital since yesterday, because he had direct contact with poultry, "said the head of the health center I Banjarangkan, Dr. Ratna, while checking health of citizens, in Hamlet Strait, Tuesday (4/2). ...

According to him, before being taken to Sanglah, named Ketut Ward patient has been given the drug Tami flu. As percegah so we do not catch bird flu.

"Preliminary results were negative, and hopefully the second test is negative," he said.

He was admitted in the next ten days will continue doing health checks of local residents. Mainly people who are in a radius of 100 meters from susfect.

Each resident will be health checked, and if the pain will be directly referred to hospitals for further from administration of.

"In addition, the animal husbandry department will also continue spraying until it is completely safe," he added....http://translate.google.com/translat...i-bali%2F49023

WHO Update-Avian influenza A (H10N8)

Avian influenza A (H10N8)


Key facts

• The WHO has been officially notified by the Chinese health authorities that avian influenza A (H10N8) has been detected in a single patient with severe pneumonia.
• The patient is a 73-year old female from Jiangxi Province, China. She was hospitalized on November 30 and died on December 6.
• This is the first ever report of H10N8 isolated from a patient.
• The patient visited a live bird market four days before date of onset. She had many underlying medical conditions (immunocompromised).
• The family members and other contacts had no symptoms and no other similar cases were detected in the area.
• The fact that the virus was isolated from a patient and reported through active surveillance by the Chinese health authorities is a sign that the surveillance system is working well.
• The specific source of the infection is unknown. As wild birds/poultry have been known to carry this virus, further sporadic cases may be detected.
• While the investigation is ongoing, including contact tracing and enhanced surveillance, so far, there is no evidence of sick contacts or human-to-human transmission.
• WHO is in contact with the national authorities and is following closely the event and will communicate important updates as they become available.

What we know

• Although China has previously detected H10N8 in wild and domestic birds, this is the first ever report of H10N8 isolated from a patient. Given the potentially unpredictable behaviour of influenza viruses, vigilance and close monitoring is needed.
• Outside of China, based on available literature, the virus had been detected in birds since 1965 in at least six countries (Italy, USA, Canada, South Korea, Sweden and Japan).
• Human infections with influenza H10N7 subtype viruses have been previously reported from Egypt and Australia. All these patients presented with mild clinical signs and recovered.
• The Chinese government is actively investigating this event and has heightened disease surveillance for early detection, prevention and control measures.
• Given the increase in ILI and SARI surveillance, testing, and subtyping of influenza A positive specimens, especially in China, it is not unexpected to start to detect human infections with a variety of non-seasonal influenza subtypes.

WHO action

• WHO is closely monitoring the situation and facilitating information sharing with Member States through the International Health Regulations.
• WHO is collaborating with animal health colleagues to identify a possible animal source of the virus and assess the health risks.
• WHO does not advise special screening at points of entry with regard to this event, nor does it recommend that any travel or trade restrictions be applied.

WHO’s public health advice

• Avoid contact with sick or dead poultry. Keep children away from poultry.
• Avoid touching any surfaces that may have been contaminated with poultry feces or blood.
• Do not eat raw or undercooked poultry. Cook poultry to internal temperature of 70°C (until meat is not pink in the centre) and do not touch cooked meat with raw meat.
• Clean cooking implements that have been in contact with raw meat before re-using.
• Wash hands regularly, especially after handling poultry, while cooking and before eating.
• Cover your mouth and nose when you cough or sneeze.
• WHO does not recommend any specific measures be applied to travellers at this time.
• Poultry, poultry products (eggs) and pork can be safely consumed provided they are properly cooked and properly handled during food preparation.

For more information, please contact

Helen Yu, Communications Officer, WHO in China, Office Tel: +86 10 65327191 ext 81275, Mobile: 13911205167, Email: yuji@wpro.who.int     http://www.wpro.who.int/china/mediacentre/factsheets/h10n8/en/index.html

Bird flu: new strain claims first victim

Tests confirm a new strain of bird flu has killed a woman in China and at least one other person is believed to be infected

...Dr Jeremy Farrar, director of the Wellcome Trust, said viruses that crossed the species barrier were always worrying because it was unlikely humans would have prior immunity.
He said: “We should be especially worried when those viruses show characteristics that suggest they have the capacity to replicate easily or to be virulent or resistant to drugs. This virus ticks several of these boxes and therefore is a cause for concern.”
But others said that with no evidence of the strain spreading from human to human, there was no cause for major alarm.

Dr Ben Neuman, a virologist at the University of Reading, said: “The patient will have had contact with tens or hundreds of friends, family, acquaintances and health care workers before the severity of the disease was apparent.
“As yet there are no reports that the virus has spread to anyone else. H10N8 fits the profile of an avian flu virus in that the disease is terrible, but the virus is not readily transmitted.” ...  http://www.telegraph.co.uk/health/flu/10617978/Bird-flu-new-strain-claims-first-victim.html

Deadly New Bird Flu Strain Spawned by Virus Behind H5N1

By Simeon Bennett Feb 4, 2014 6:30 PM ET

The new bird flu that’s infected two people in China, killing one, was spawned by the same pathogen that produced two other deadly flu strains, a study found.
The new H10N8 strain, which hasn’t previously been reported in humans, contains six out of eight....
 ....H10N8 contains a mutation that helps it adapt to mammals, and may enable the virus to become more infectious, the researchers, led by Yuelong Shu at the Chinese Center for Disease Control and Prevention, wrote.
“The pandemic potential of this novel virus should not be underestimated,” Shu and colleagues wrote. “Although we cannot predict whether an H10N8 epidemic will occur, our findings suggest that the virus is a potential threat to people.”
The dead woman had visited a live poultry market a few days before becoming unwell, though the virus wasn’t found in samples collected later from the market and the source of infection remains unknown, the researchers said...  http://www.bloomberg.com/news/2014-02-04/deadly-new-bird-flu-strain-spawned-by-virus-behind-h5n1.html

Scientists talk of 'pandemic potential' after first confirmed human death from new strain of bird flu

Elderly woman from south east China is the first casualty of a worrying new strain, called H10N8

Chinese scientists have said the “pandemic potential” of a new strain of bird flu “should not be underestimated” after the first known human infection resulted in the death of an elderly woman.

The new strain is a variant of a virus known as H10N8, which scientists believe may have originated in wild birds, and later spread to poultry.
The victim, a 73-year-old woman from Nanchang City in south-eastern China, was the first person confirmed to have been infected with the new type, and a second case has since been discovered, raising concerns that the virus has evolved so that it can transfer easily from birds to humans.
Its emergence coincides with a surge in the number of cases of another bird flu strain, H7N9, which is known to have infected 286 people since March last year, causing 60 deaths. The vast majority of cases have occurred in China, but Taiwan has also recorded two infections, and the virus is known to have spread to Hong Kong, which has seen four cases....
In their report of the death, published in The Lancet medical journal today, public health scientists in China said that it “further increases the importance of surveillance for pandemic preparedness and response”, adding that “the pandemic potential of this novel virus should not be underestimated".
However, Dr John McCauley, director of the World Health Organisation’s Collaborating Centre for Influenza, said that the “epidemiological significance” of the infection remained “unclear”.
“Previously we did not think that H7N9 infections might be so lethal,” he said, referring to fatal cases in China. “Now we also must consider H10N8 as well.”
“More human infections by avian H10N8 cannot be ruled out,” he said, adding that the virus did not cause serious di..  http://www.independent.co.uk/life-style/health-and-families/health-news/scientists-talk-of-pandemic-potential-after-first-confirmed-human-death-from-new-strain-of-bird-flu-9107345.html

Health union accuses of lying .. 9 injured doctors infected with the flu and the death of four of them .. The ministry hide the true numbers of patients

Tuesday, February 4th, 2014 - 11:07:51 PM

"Doctors" calling for "health" to form a committee to discuss the acute respiratory infections in hospitals
Veterinary services did not reach so far into foci infected with swine flu
"Health" to hide the true numbers of patients .. Health and revealing cases

Severe crisis erupted between the Medical Association and the Ministry of Health after the union accused the ministry of lying with respect to injury doctors infected with the flu and the death of four people, including.

And held the Medical Association, held a press conference Tuesday afternoon, the House of Wisdom to discuss the recurrence of deaths among doctors respiratory syndrome in the recent period where he has been advocating for each of the union and the Ministry of Health and the World Health Organization and the Bootleg to attend the conference.

He denied Dr Khaled Samir board member of the Medical Association, what was said by the Ministry of Health said that the doctors who have died as a result of severe acute respiratory infection were suffering from other diseases.

He said on the sidelines of the press conference held today syndicate about recurrence and mortality doctors that the Ministry of Health has always practiced lying and irresponsible statements, pointing out that the officials of the ministry they exile daily on the pages of newspapers that are no any infection or virus infects patients from hospitals, this is not true.

He pointed out that the union had already warned by the ministry of the seriousness of this virus, but it did not do any steps, and was the result of this announcement today about the death of more than 24 cases as a result of this virus and injuring more than 100 people.

As for the number of HIV-infected doctors explained, "Samir" There are 9 cases among doctors were injured as a result of severe acute respiratory respiratory infections and 4 cases of them died.

It was announced that the union has demanded that the Ministry of Health set up a committee comprising experts and professors from the University of search and examination of the infected cases where the union by 50 000 university professor, but the ministry ignored this requirement.

The student ministry of the need to recognize that there is a problem and a virus that could kill many people, not just doctors.

The Ministry of Health and Population has announced today that the injury of 7 doctors only severe acute respiratory only two of them afflicted with influenza The rest of the doctors They were suffering from other diseases.

Declared Dr. Mona Mina, Secretary-General of the Medical Association that "the union has already addressed the Ministry of Health and Population for the formation of a fact-finding committee to discuss the crisis injury patients and doctors Acute Respiratory Syndrome."

Said Mina, during the press conference which was held today, Tuesday, Medical Association, "It is medically known that severe acute respiratory syndrome infected by the injury to the elderly, but a number of doctors who are at a young age is a risk that must be recognized."

She added that "the union does not have Labs until you alone to examine this issue, but what it has done is to sound the alarm to the Ministry of Health, which has ignored the demands of the doctors of the need to form committees to discuss the cases," noting that "the Ministry of Health has responded to the union that the doctors are the cause of the infection due to lack of wearing masks, despite the fact that doctors are committed to all means of prevention of infection. "

Mona Mina and demanded the need to recognize that the Ministry of Health of the problem, and that is the formation of committees of infection control in hospitals and to see cases examined.

Dr Sami Taha captain veterinarians, "The veterinary services did not reach so far into foci infected with" HP and that and that "otherwise known as swine flu."

The captain veterinarians, during the conference that "the medical departments located at the level of Egypt, there are teams for rapid deployment of veterinarians who examined the outposts, which are reported and make sure it is infected with bird flu or swine, and then be communicated to the Ministry of Health for these spots."

He stressed that "the union has issued several recommendations to control the problem of influenza infection and most importantly the formation of a database and information from all sides about the flu", criticizing the lack of a database of flu in Egypt.

He called the togetherness of all parties to monitor and check the virus and determine the cause of the disease, and the provision of effective antibiotics to treat the flu virus, as well as the application of this system of monitoring and follow-up of cases infected with the virus.

Dr Ahmed Hussein, a member of the Council of the Doctors' Union, said that "the Ministry of Health revealing the cases that suffered as a result of severe acute respiratory flu within the hospital, and did not declare the true figures for the injured."

He said, "Hussein" that "there are cases appeared provinces of Zagazig and Dakahlia not announced by the Ministry of Health," pointing out that "the union has contacted the Ministry of Health since the death of the doctor first, Dr. Ahmed Abdel Latif, who died as a result of infection of respiratory."

In response to a statement by the Ministry of Health that the doctors of the deceased, who died as a result of other diseases, he wondered: "It has examined these cases and I am confident to hit other illnesses," adding that "doctors treating the cases are assured that their injuries infected with respiratory inside Alospat led to the hit by severe acute respiratory which led to their status on a respirator. "

Hussein demanded the necessity of forming a special committee to discuss the causes of injuries and diagnose the condition and methods of prevention and treatment of them. http://translate.google.com/translate?sl=ar&tl=en&js=n&prev=_t&hl=en&ie=UTF-8&u=http%3A%2F%2Falmogaz.com%2Fnews%2Fpolitics%2F2014%2F02%2F04%2F1325291

«Health» Beni Suef denies death cases because of injuries b «avian flu»

Posted on: Tuesday, February 4th, 2014 - 19:14 | Last updated: Tuesday, February 4th, 2014 - 19:14

Infected with bird flu

Wrote: Hazem Kholi

Denied, Dr. Ahmed Anwar, Undersecretary of the Ministry of Health in Beni Suef, published some «websites» for the death of two preservation after they got infected with bird flu.

 

The agent said the Ministry of Health «The first case (the deceased) to a student 15 years resident in the village Ashment of the Center for Nasser north of the province, entered the hospital health insurance evening of January 22, infected with acute pneumonia and poisoning of the blood, was admitted to the Department of Internal Medicine at the hospital until January 25, was transferred to intensive care at the hospital, and remained until 27 of the same month, a sample was taken from the throat and blood samples were sent to the central laboratories of the ministry, which confirmed that the result is negative and is not infected with bird flu, adding «The cause of death of the student is not bird flu, but the resulting for the failure in the functions of breathing resulted in the presence of antenna combines crystalline membrane, resulting in a sharp drop in blood circulation and cardiac arrest ».

 

He said Anwar said that the second case of a housewife called 30 years old, "a resident in Semsta entered the hospital diets to maintain infected with pneumonia, and was suspected to be infected by bird flu, blood samples were taken and sent to the laboratories of the ministry, and also proved negative and not infected with the disease, and was transported to the hospital Abbasid in Cairo , and discharged from the hospital on Jan. 30 after her condition improved and she returned to her home, and you communicate with them and to check on her condition ».

 

The Anwar «Today is suspected in the case of a new child is 5 years old in the village of medicines of the city of Beni Suef infected with acute pneumonia, was detained health insurance hospital, blood samples were taken and sent to the central laboratories of the ministry». http://translate.google.com/translate?sl=ar&tl=en&js=n&prev=_t&hl=en&ie=UTF-8&u=http%3A%2F%2Fwww.shorouknews.com%2Fnews%2Fview.aspx%3Fcdate%3D04022014%26id%3D6c874acb-e381-404e-8056-cbc0a70d236f   

Two women killed by bird flu, despite denials by the Department of Health injury

Tuesday February 4, 2014

A state of resentment and anger in Beni Suef to the Department of Health, following the death of two cases, on Tuesday morning, the province's hospitals after being denied Directorate of contracting bird flu virus.

For its part, the Department of Health announced in Beni Suef is not infected with bird flu cases, and that the disease is a pneumonia-like symptoms, but bird flu - a statement by the Directorate.

He said Dr Anwar Ahmad, Undersecretary of the Ministry of Health in Beni Suef, that the samples that were sent to the laboratories of the ministry in Cairo were negative and confirmed the lack of contracting the disease.  http://translate.google.com/translate?sl=ar&tl=en&js=n&prev=_t&hl=en&ie=UTF-8&u=http%3A%2F%2Famlalommah.net%2Fnew%2Findex.php%3Fmod%3Darticle%26id%3D47592

China- Poultry industry request to stop every #H7N9 case notification

Poultry industry request to stop every case notification

At 00:59 on February 5, 2014 Beijing Times

According to Xinhua News Agency February 4 electric Recently, Guangdong, Guangxi and even the National Poultry Industry Association and companies have jointly submitted an open letter to the government at all levels, the demands of letters, a clear request "to stop the implementation of each notification H7N9 cases, to avoid the outbreak of super-density reports. " The health department, said no legal basis, does not help.
National Health and Family Planning Commission October 28, 2013 on the adjustment part of the statutory management of infectious disease, the inclusion of human infection with H7N9 avian influenza B infectious legal. Poultry Industry Association, the companies believe that the H7N9 downgrade, should not be unduly released epidemic, driven by excessive media coverage.
Guangdong, the largest agricultural enterprises in Guangdong Wen's Food Group Co., Ltd. Wen Pengcheng said, according to the National Planning Commission released guard in December 2013 of notifiable infectious diseases nationwide overview shows ranking of viral hepatitis, tuberculosis, and its infectious and the risk of dying than the H7N9 flu virus is high, but then H7N9 adopt unconventional measures involving practitioners and industry is not fair.
Guangdong health department official said in an interview responses, H7N9 although B infectious diseases in our country has been included in the management, but WHO (World Health Organization) regulations have clear provisions for emerging infectious diseases, each case must be informed of subtype . Since China joined WHO, must comply with the appropriate rules. Health sector insiders who asked not to be named, said: "For the loss suffered by the poultry industry, and no one worried, but not informed of sympathy and new cases, no legal basis, does not help, open and transparent with the government emergency information. contrary. "
Health sector expert who requested anonymity suggested that the poultry industry to reduce its exposure of the epidemic, as some idea of ​​updating, such as the promotion of "centralized breeding, slaughtering concentrate, chilled listed" mode, reducing the opportunity for direct contact with live poultry .
The industry believes that, in the event of a public health and safety, government responsibility should also be clear. Jianfeng and other CDC experts believe that other measures in live bird markets closed, the aquaculture industry to public health and safety made a great contribution to the Government's responsibility thanked aquaculture and compensation, but we can not simply allow farmers to bear the loss. http://translate.googleusercontent.com/translate_c?depth=1&hl=en&ie=UTF8&prev=_t&rurl=translate.google.com&sl=zh-CN&tl=en&u=http://news.sina.com.cn/o/2014-02-05/005929398176.shtml&usg=ALkJrhiLqQ-xaaCn8ME3YWao-y92-qcHxA

Human infection with avian influenza A(H7N9) virus –WHO update

Disease outbreak news

4 February 2014 - On 2 February 2014, the National Health and Family Planning Commission (NHFPC) of China notified WHO of five additional laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus including one death.

Details of the cases are as follows:

Four cases are male. The age range is 8 to 63 years old. Cases have been reported from Guangdong (2), Hunan (1), Fujian (1) and Zhejiang (1). Three cases are currently in serious condition, one in critical condition. All cases are reported to have had exposure to poultry or a live poultry market.

• A 44 year-old man from Taizhou City, Zhejiang Province, who became ill on 28 January and was admitted to hospital on 31 January. He is currently in a serious condition. The patient has a history of exposure to live poultry.
• A 8 year-old girl from Yongzhou City, Hunan Province, who became ill on 30 January and was admitted to hospital on 31 January. She is currently in a serious condition. The patient has a history of exposure to a live poultry market.
• A 35 year-old man from Xiamen City, Fujian Province, who became ill on 27 January and was admitted to hospital on 1 February. He is currently in serious condition. The patient has a history of exposure to live poultry.
• A 37 year-old man from Zhongshan City, Guangdong Province, who became ill on 26 January and was admitted to hospital on 29 January and then transferred to the another hospital on 30 January. He is in a critical condition. He has a history of exposure to a live poultry market.
• A 63 year-old man from Shenzhen City, Guangdong Province, who became ill on 27 January and was admitted to hospital on 1 February and died on the same day. The patient had a history of exposure to a live poultry market.

So far, there is no evidence of sustained human-to-human transmission.
The Chinese Government continues to take the following surveillance and control measures:

• strengthen surveillance and situation analysis;
• reinforce case management and treatment;
• conduct risk communication with the public and release information;
• strengthen international collaboration and communication; and
• conduct scientific studies.

Sporadic human cases

While the recent report of avian influenza A(H7N9) virus being detected in live poultry imported from the mainland to Hong Kong SAR, shows the potential for the virus to spread through live poultry, at this time there is no indication that international spread of avian influenza A(H7N9) has occurred through humans or animals.
Further sporadic human cases of A(H7N9) infection are expected in affected and possibly neighbouring areas, especially given expected increases in the trade and transport of poultry associated with the Lunar New Year.

WHO advice

WHO advises that travellers to countries with known outbreaks of avian influenza should avoid poultry farms, or contact with animals in live bird markets, or entering areas where poultry may be slaughtered, or contact with any surfaces that appear to be contaminated with faeces from poultry or other animals. Travellers should also wash their hands often with soap and water. Travellers should follow good food safety and good food hygiene practices.
WHO does not advise special screening at points of entry with regard to this event, nor does it currently recommend any travel or trade restrictions.
As always, a diagnosis of infection with an avian influenza virus should be considered in individuals who develop severe acute respiratory symptoms while travelling or soon after returning from an area where avian influenza is a concern.
WHO encourages countries to continue strengthening influenza surveillance, including surveillance for severe acute respiratory infections (SARI) and to carefully review any unusual patterns, in order to ensure reporting of human infections under the IHR (2005), and continue national health preparedness actions.

Current technical information as well as guidance related to avian influenza A(H7N9) can be found at the WHO web site:

• Avian influenza A(H7N9) virus
• Human infections with avian influenza A(H7N9) virus
  pdf, 194kb
  21 January 2014
• World - Avian influenza in humans  

 http://www.who.int/csr/don/2014_02_04/en/index.html

During the conference of the Medical Association for the swine flu .. Mina: faced with an unusual virus kills young doctors in a short period

Tuesday, February 4th, 2014 14:29

Mona Mina

Started - Faten Khedive and Mayada Ashraf

Said Dr. Mona Mina: There is a phenomenon which is the spread of pneumonia as a result of the virus do not know the number of deaths among young doctors, pointing out that the pneumonia leading cause of death among newborn children or elderly people or from taking certain treatments affect immunity, but what we are seeing now is a virus pneumonia kills an extraordinary young doctors in a short period and this is unusual, noting that this phenomenon deserves attention.
She noted during her conference journalist held now the House of Wisdom, about a repeat of deaths among doctors pneumonia in recent times, the need to follow the procedures for surveillance and vaccination of doctors and outreach to citizens and to deal seriously with an important phenomenon, saying: We do not overdramatize of the case, but we deal with it seriously.
She explained that the past years have not Atov four doctors claim the Ministry of Health to deal seriously with injuries pneumonia and availability of information and infection control procedures.
And demanded that the Ministry of Health, regardless of compensation and pensions exceptional physicians deceased as a result of injury at work, as a result of failure to implement programs to combat infection, pointing out that the ministry is now cooperating in transforming doctors in need of care, and claim the issuance of a ministerial decision to treat doctors to hospitals that provide good care.http://translate.google.com/translat...25B1%25D8%25A9

Egyot-Hay: 6 injuries among doctors pneumonia

---

Hay: 6 injuries among doctors pneumonia

Dr. Osama Abdel Hay, secretary of the Medical Association, the doctors increased acute respiratory infections in the recent period, pointing out that the first death was Dr. Ahmed Abdul Latif in 12/21/2013.
According to Abdel Hay, - during a conference of the Medical Association to discuss the recurrence and mortality doctors pneumonia - that the union demanded that the ministry of trying to move the doctor to the hospital with special attention to the treatment of severe acute respiratory syndrome, and the work of the necessary tests, but they did not respond, but declared that the tests did not prove the existence of a particular disease of death.

Abdel Hay confirmed that cases of the disease in the growing and reached'm not cases of them died of the disease four cases and one case of swine flu virus has.
He explained Abdel Hay, the main issue as the transparency of the information provided to the responsibility of the Ministry of Health how to deal with the disease, and expressed his dismay at the charge of the union ministry exaggerating the situation, which is unacceptable.http://translate.google.com/translat...2588%25D9%2589

1st New Human Case of Avian Influenza H5N1 in Cambodia in 2014

The Ministry of Health (MoH) of the Kingdom of Cambodia wishes to advise members of the public that one new human case of avian influenza has been confirmed for the H5N1 virus. This is the 1st case of this year and the 48th people to become infected with the H5N1 virus in Cambodia. Case is from Kampong Thom province and he is currently in a stable condition. Of the 48 confirmed cases, 36 were children under 14, and 27 of the 48 were female. In addition, since the first case happened in Cambodia in 2005 there were only 16 cases survived.

The 1st case this year, a 5-year-old boy from Chongda village, Tbaung Kropeur commune, Santuk district, Kampong Thom province, was confirmed positive for H5N1 human avian influenza on 1st February 2014 by Institut Pasteur du Cambodge. The boy had onset fever and headache on 24th January 2014, his parents sought treatment at a private clinic on 27th January with symptoms of high fever and cough, but his condition worsened. The boy was admitted to Jayavarman VII Hospital, Siem Reap, on 30th January 2014. Tamiflu was administered on 31st January.

Investigations in the village by the Ministry of Health’s Rapid Response Teams (RRT) and the Ministry of Agriculture, Forestry and Fishery’s (MAFF) Animal Health Task Force revealed that around 200 chickens died suddenly mid-January. The boy’s parents and relatives prepared the dead chickens for food while the boy stayed around the area..........

http://www.cdcmoh.gov.kh/PressReleas...5N1_Eng_v1.pdf

Egypt-3 suspected cases of bird flu in Minia

3 suspected cases of bird flu and queens

---

Today prevailed severe case of panic among the local people in Minia Governorate after widespread reports of the emergence of 3 cases of bird flu, Matay center north of the province.
The request said Jamal Mahmoud, a resident of Center Matay they were surprised yesterday emergence of 3 cases of bird flu, and a lot of people's slaughter of large numbers of infected birds, and queues lined up in front of the veterinary unit.

The official confirmed the Directorate of Veterinary Medicine in Minia Governorate was injured in suspected cases of three bird flu samples were taken from infected birds, was to make sure they are free of the virus, but people's condition were very dismayed by the emphasis on them that the result is negative.

Rushed a lot of parents to pharmacies to search for drug Altamflo anti-virus for fear of moving to the people and turn into an epidemic.

http://translate.google.com/translat...258A%25D8%25A7