On March 31, the National Health and Family Planning Commission Bulletin, found three cases of human infection with the H7N9 avian influenza in Shanghai and Anhui. This is a worldwide first discovery of human infection with the H7N9 virus, the virus previously found only in poultry between.
Under the notification, in the three cases, the 87-year-old male patient Lee onset on February 19; March 29, the Chinese Center for Disease Control H7N9 avian influenza virus isolated from the cases.
The public, of H7N9 cases after the Shanghai Municipal Health Bureau and treatment for the above named Li patients Shanghai 5th People's Hospital (hereinafter referred to as the "Court") "rumor" action surfaced.
on March 7, the five branches of the Shanghai Municipal Health Bureau has said through the official microblogging network transmission, Minhang District, unexplained deaths Xiaoxibushi, has ruled out the 87-year-old son Lee and two human bird flu infection and other infectious diseases. The rumor issued on expert opinion also cited, Lee, and their youngest son was killed, "suffering from a number of basic diseases, together with the lungs severe infection caused".
Health and Family Planning Commission, however, in the Question and Answer issued on March 31, but indirectly deny the rumor information, said in the February 20 to 25, in a hospital in Shanghai has admitted suffering from severe pneumonia, surnamed Li, father and son 3 people, 2 people died after the rescue. surnamed Li, his father was diagnosed with the H7N9 avian influenza virus infection. "
"We are only informed of the news found two cases of H7N9 avian flu cases in Shanghai," a female staff member in the Office of the five branches of the interview with this reporter, said, "has not yet received the official notification, and therefore can not be comment infected with the H7N9 bird flu virus, the 87-year-old Lee was detected, the patient whether previously admitted to our hospital. "
The staff also said that the process according to standard treatment, the hospital in the early morning of February 26, activation of the plan, reported Minhang District CDC collection and do the epidemiological investigation, test results, "and I do not know the details".
Shanghai Municipal Health Bureau, the Propaganda Department declined the newspaper interview apply to said the H7N9 virus council will be announced to the public through the website.
Shanghai Municipal Government, a special meeting to be held on April 1, the deployment of the H7N9 avian flu prevention and control work. Vice Mayor Shen Xiaoming attended the meeting to ask all departments to attach great importance to go all out in close collaboration, active prevention and control of human infection with the H7N9 avian influenza. Health departments should further strengthen the city influenza unexplained cases of pneumonia and other respiratory monitoring of infectious diseases prevention and control efforts.
Meeting clear and municipal levels of medical and health institutions to regulate the management of fever clinics, highly concerned about the cases of pneumonia with similar symptoms, and to discover and press norms do case reports, sample collection, laboratory testing and medical treatment.
In accordance with the requirements of the Veterinary Bureau of the Ministry of Agriculture and Agriculture Commission, the City Animal CDC April 1 of the recent salvaged the upper reaches of the Huangpu River floating dead pig sampling 34 retained samples for the detection of avian influenza universal primers, not found in poultry influenza virus.
Virus was misdiagnosed?
The afternoon of March 7, a microblogging messages are forwarded dissemination of content called "the Fifth People's Hospital of Shanghai a few cases of unidentified deaths initially diagnosed as influenza, respiratory failure symptoms, hospital publish the truth", followed by this the microblogging is deleted released microblogging users to change the account name.
The information in the day have been the five branches of the Shanghai Municipal Health Bureau denied.
17:20 the same day, the five branches of the official microblogging network transmission unexplained deaths events truth ", said the period from February 14 to 24, surnamed Li, a family of three with a high fever, cough, have come to hospital, 87-year-old Lee senior citizens multiple organ failure, and died of his wounds on March 4; 55-year-old Lee, the youngest son died of his wounds on February 28 due to severe pneumonia, respiratory failure "; 69-year-old son in stable condition .
After about an hour, the Shanghai Municipal Health Bureau through the official microblogging further said that City Hospital has admitted a family of three, epidemiological investigation and laboratory detection, has been ruled out of human avian influenza and other infectious diseases. Experts believe that two people died due to suffering from a number of basic conditions, coupled with the lungs severe infections caused by.
Health and Family Planning Commission briefing on March 31 have shown that the 87-year-old surnamed Li, male patients infected with the H7N9 virus. Its incidence on February 19 and March 4, died after active rescue.
Shanghai Municipal Health Bureau said on March 31, Lee before the onset of his two sons are also due to similar symptoms to the hospital for treatment, the eldest son was diagnosed with a lung infection, pneumonia, has been cured; youngest son was diagnosed with severe pneumonia, after she died. The two sons were not detected H7N9 avian influenza.
This shows that the National Health and Family Planning Commission and the Shanghai Municipal Health Bureau on March 31 have been confirmed, the 87-year-old surnamed Li male patients indeed infected with newly discovered human infection with the H7N9 avian flu virus, rather than after the five branches and Shanghai Health Bureau alleged human avian influenza and other infectious diseases has been ruled out.
A noteworthy detail is the recognized expert consultation on behalf of the five branches of the press release issued on March 7, three patients are pneumonia.The manuscripts also said that the inspection by the Shanghai Public Health Clinical Center, excluded patients such as highly pathogenic avian influenza "atypical pneumonia".
In reply to this hospital misdiagnosis, a staff member of the five branches of the Publicity Bureau, Lee did not the influenza A (H1N1) infection as a statutory infectious diseases and human infection of highly pathogenic avian influenza (H5N1 ), March 7, five institutes said "exclude avian influenza virus infection, probably referring to is the H5N1 virus, rather than the time has not yet been laboratory findings, be human infection of H7N9 virus.
Newspaper reporter access to the relevant laws and regulations, the former Ministry of Health recently identified statutory infectious diseases, contains only the H1N1 and H5N1 avian influenza virus, did not contain the H7N9 virus.
Informed why so slow
Found close contacts 3 and above in accordance with the provisions of treatment similar to the disease, the hospital will consider whether they are infected with contagious diseases, of the five branches of the office staff said the reporter, "Mr Lee, a family of three to hospital, the hospital is also in accordance with the standards process to Minhang District Center for Disease Control informed. "
The staff further said that five homes do not have the monitoring capabilities of all infectious diseases virus serum of patients through the hospital acquisition, by Shanghai or national disease control departments to carry out serological screening.
Bulletin released by the Shanghai Municipal Health Bureau show that the five branches of public health has to the City Center and the City of clinical disease prevention and control center for inspection from patients Lee, two centers to carry out laboratory screening excluded seasonal flu Influenza A H1N1 flu, people infected with the highly pathogenic avian influenza (H5N1) and SARS, novel coronavirus might. In further testing, it is found that the patient may be infected can not be sub-type of influenza virus. Recognized after the detection of the China Disease Prevention and Control Center for Influenza A H7N9 avian flu virus.
"In the afternoon of March 29, the Chinese Center for Disease Control isolated from samples of related cases to the H7N9 bird flu virus," Health and Family Planning Commission said in a briefing, "March 30, the National Health and Family Planning Organization experts diagnosed three patients with human infection of H7N9 avian influenza confirmed cases, according to the clinical manifestations, laboratory testing and epidemiological findings.
From Lee onset to 32 days after notification of cases, Health and Family Planning Commission, the public questioned the delay in reporting the outbreak.The Committee on March 31 and informed at the same time open the question-and-answer, questioned targeted reply, said that the H7N9 avian influenza virus, is the world's first discovery of a new subtype of influenza virus, has not been included in our statutory report infectious disease monitoring and reporting system. "
This question-and-answer release also revealed that the Shanghai Public Health Clinical Center patients may be infected with the H7 influenza was discovered on March 22, after specimens were sent to the China Disease Prevention and Control Center. On the afternoon of March 29, the Chinese Center for Disease Control three H7N9 avian influenza virus isolated from the submission of cases specimens. National Health and Family Planning Organization experts further verification, according to laboratory test results, combined with the clinical manifestations, epidemiological data to conduct a comprehensive analysis to determine the patients with human cases of infection with the H7N9 avian flu virus.
According to the time node from the five branches of the Minhang District CDC report on the disease and to collect samples, after layers of newspaper delivery to Shanghai Public Health Clinical Center, and then from the center to the relevant agencies of the national level to the patient-related specimens This period lasted 24 days. In this process, the relevant departments of Shanghai can not exactly test the specific type of virus infection by Lee.
The official website of the Shanghai Public Health Clinical Center, the Center of Fudan University tertiary hospitals, or national infectious disease physician continuing education training base, clinical base of Shanghai Municipal Center for Disease Control, and the Department of Infectious Diseases known.
According to this reporter learned that the current domestic laws and regulations for infectious diseases, mainly by the Communicable Disease Prevention Law of the People's Republic of China "and the former Ministry of Health issued in 2006 and 2012, the second of two documents.
The former Ministry of Health issued in 2012, the second of the General Office of the Ministry of Health on the issuance of the notification of outbreaks of influenza-like illness Disposal Guide (2012 edition), "clearly, the same schools, preschools, or other collective units in 1 week ILI cases above death, after verification, the county level disease prevention and control institutions, should be reported through public health emergency management information system within 2 hours, Influenza Surveillance Network Laboratory received outbreaks specimens requires within 24 hours of influenza virus subtype identification network laboratory with influenza virus isolation of influenza virus nucleic acid testing positive specimens for virus isolation.
The interpersonal whether infection remains to be verified
On March 31, the World Health Organization (WHO) Blue Ruiming (Timothy O'Leary), a spokesman for the regional offices in Manila, said the WHO is closely monitoring the development of the situation.
"(H7N9 virus), it seems there is no evidence of infection in the interpersonal and virus infection may seem inefficient, seems to lower the threat to public health." Blue Ruiming told the media.
The National Health and Family Planning Commission also cited the expert view is that, according to who is in close contact with medical observation, not suggesting that the virus has a strong human-to-human transmission.
"This is the world's first such strains isolated from humans, according to the Academy of Medical Sciences of the biological properties of influenza virus gene information analysis platform analysis of this strain in the spread of power in the world, should not be very strong," Zhejiang Academy of Medical Sciences Guo Chao Tan, director of the Institute of Biological Engineering, the media said, "because H7N9 strains isolated in humans for the first time, we do not yet vaccine, if infected, what drugs can be treated effectively, but also need to be studied."
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